Early into her acting career she appeared in Rockhopper, an unsold CBS TV-Pilot from 1985. Yasbeck has had guest starring roles in many television shows including Dallas, Spies, Werewolf, J.J. Starbuck, Magnum, P.I., China Beach and Murphy Brown. She played Olivia Reed for four months between 1986-1987 on the long-running daytime soap opera Days of Our Lives. She also played the part of Madison the mermaid in the Disney television movie Splash, Too in 1988 (the role of Madison was originated by Daryl Hannah in the 1984 movie Splash). Playing a mermaid in Splash, Too was a fulfillment of a childhood dream for Yasbeck as she loved mermaids when she was a little girl at 5 years old after watching a Disney movie that featured mermaids. Yasbeck has also had starring roles in the sitcoms Wings, Alright Already, and Life on a Stick and in movies such as House II: The Second Story, Pretty Woman, Problem Child, Problem Child 2 and The Mask. She has twice worked with Mel Brooks, in 1993’s Robin Hood: Men in Tights and 1995’s Dracula: Dead and Loving It.
In late 2007, plans surfaced of a potential That’s So Raven spinoff featuring Yasbeck and Anneliese van der Pol, who portrayed her daughter, with occasional appearances by Raven-Symoné. The show was scrapped due to van der Pol signing onto a new Broadway play, and Yasbeck wanting to take a break from acting to focus on her family.
She was a contestant on Are You Smarter Than a 5th Grader? in 2010.